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  • New drug to regenerate lost teeth

    Scientists report that an antibody for one gene -- uterine sensitization associated gene-1 or USAG-1 -- can stimulate tooth growth in mice suffering from tooth agenesis.

  • People with severe gum disease may be twice as likely to have increased blood pressure

    Research shows that periodontitis, severe gum disease, is linked to higher blood pressure in otherwise healthy individuals. This study of 500 adults with and without gum disease found that approximately 50% of adults could have undetected hypertension. Promotion of good oral health could help reduce gum disease and the risk of high blood pressure and its complications.

  • How teeth sense the cold

    An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches.

  • Scientists find evidence that novel coronavirus infects the mouth's cells

    Scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. The findings point to the possibility that the mouth plays a role in transmitting SARS-CoV-2 to the lungs or digestive system via saliva laden with virus from infected oral cells. A better understanding of the mouth's involvement could inform strategies to reduce viral transmission within and outside the body.

  • Dentists' tool boost as engineers get to root of tiny bubbles

    People's teeth-chattering experiences in the dentist's chair could be improved by fresh insights into how tiny, powerful bubbles are formed by ultra-fast vibrations, a study suggests.

  • Periodontal disease increases risk of major cardiovascular events

    People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research.

  • New hope for treating chronic pain without opioids

    According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients -- a frustration that's often compounded by a hesitation to prescribe opioids for pain.

  • Bleeding gums may be a sign you need more vitamin C in your diet

    Bleeding of the gums on gentle probing, or gingival bleeding tendency, and also bleeding in the eye, or retinal hemorrhaging, were associated with low vitamin C levels in the bloodstream.

  • Ancient proteins help track early milk drinking in Africa

    Got milk? The 1990s ad campaign highlighted the importance of milk for health and wellbeing, but when did we start drinking the milk of other animals? And how did the practice spread? A new study led by scientists from Germany and Kenya highlights the critical role of Africa in the story of dairying, showing that communities there were drinking milk by at least 6,000 years ago.

  • Research establishes antibiotic potential for cannabis molecule

    The main nonpsychoactive component of cannabis has been shown to kill the bacteria responsible for gonorrhoea, meningitis and legionnaires disease, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.

  • Research shapes safe dentistry during COVID-19

    Research has been used to shape how dentistry can be carried out safely during the COVID-19 pandemic by mitigating the risks of dental aerosols.

  • Gum disease-causing bacteria borrow growth molecules from neighbors to thrive

    The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new study.

  • Dental experts discover biological imbalance is the link between gum and kidney disease

    An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study has found.

  • The incredible, variable bacteria living in your mouth

    Researchers have examined the human oral microbiome and discovered tremendous variability in bacterial subpopulations living in certain areas of the mouth. In many cases, the team was able to identify a handful of genes that might explain a particular bacterial group's habitat specificity.

  • Coronavirus spread during dental procedures could be reduced with slower drill rotation

    Researchers have found that careful selection and operation of dental drills can minimize the spread of COVID-19 through aerosols.

  • How poor oral hygiene may result in metabolic syndrome

    Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.

  • Reversible stickiness is something to smile about

    Researchers report a cross-linker for dental cement that breaks down under UV light, making treatments easier to reverse.

  • Can we make bones heal faster?

    A new article describes for the first time how minerals come together at the molecular level to form bones and other hard tissues, like teeth and enamel.

  • Teeth grinding and facial pain increase due to coronavirus stress and anxiety

    The stress and anxiety experienced by the general population during Israel's first lockdown brought about a significant rise in orofacial and jaw pain, as well as jaw-clenching in the daytime and teeth-grinding at night, according to a new study.

  • Most dentists have experienced aggression from patients

    Roughly half of US dentists experienced verbal or reputational aggression by patients in the past year, and nearly one in four endured physical aggression, according to a new study.

  • A tiny jaw from Greenland sheds light on the origin of complex teeth

    Scientists have described the earliest known example of dentary bone with two rows of cusps on molars and double-rooted teeth. The new findings offer insight into mammal tooth evolution, particularly the development of double-rooted teeth.

  • Mechanical forces of biofilms could play role in infections

    Studying bacterial biofilms, scientists have discovered that mechanical forces within them are sufficient to deform the soft material they grow on, e.g. biological tissues, suggesting a 'mechanical' mode of bacterial infection.

  • Light stimulation makes bones heavier

    Researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery.

  • Researchers demonstrate how changing the stem cell response to inflammation may reverse periodontal disease

    Scientists have discovered that a specific type of molecule may stimulate stem cells to regenerate, reversing the inflammation caused by periodontal disease.

  • Breakthrough for tomorrow's dentistry

    New knowledge on the cellular makeup and growth of teeth can expedite developments in regenerative dentistry - a biological therapy for damaged teeth - as well as the treatment of tooth sensitivity.

  • Researchers ask: how sustainable is your toothbrush?

    Researchers have examined the sustainability of different models of the most commonly used oral health product - the toothbrush - to ascertain which is best for the planet and associated human health.

  • Polymers prevent potentially hazardous mist during dentist visit

    If the mist in a dentist's office -- sent flying into the air by spinning, vibrating tools -- contains a virus or some other pathogen, it is a health hazard. So researchers studied the viscoelastic properties of food-grade polymers and discovered that the forces of a vibrating tool or dentist's drill are no match for them. Not only did a small admixture of polymers completely eliminate aerosolization, but it did so with ease.

  • Stopping tooth decay before it starts -- without killing bacteria

    Eating sugar or other carbohydrates after dental cleanings causes oral bacteria to quickly rebuild plaque and to produce acids that corrode tooth enamel, leading to cavities. Today, scientists report a treatment that could someday stop plaque and cavities from forming in the first place, using a new type of cerium nanoparticle formulation.

  • Cancer mutations caused by bacterial toxin preventable

    Reports show that cancer is the second leading cause of death globally. Scientists have found DNA mutations in some cancers that link them to a bacterial toxin called colibactin. Their findings improve understanding of how some cancers develop, and could help in their prevention.

  • Atomic force microscopy reveals nanoscale dental erosion from beverages

    Researchers used atomic force microscopy to quantitatively evaluate how acidic and sugary drinks affect human tooth enamel at the nanoscale level. This novel approach is useful for measuring mechanical and morphological changes that occur over time during enamel erosion induced by beverages.

  • Smile: Atomic imaging finds root of tooth decay

    Researchers combined complementary imaging techniques to explore the atomic structure of human enamel, exposing tiny chemical flaws in the fundamental building blocks of our teeth. The findings could help scientists prevent or possibly reverse tooth decay.

  • Gum disease may raise risk of some cancers

    People who have periodontal (gum) disease may have a higher risk of developing some forms of cancer.

  • Robot jaws shows medicated chewing gum could be the future

    Medicated chewing gum has been recognized as a new advanced drug delivery method but currently there is no gold standard for testing drug release from chewing gum in vitro. New research has shown a chewing robot with built-in humanoid jaws could provide opportunities for pharmaceutical companies to develop medicated chewing gum.

  • Materials scientists drill down to vulnerabilities involved in human tooth decay

    Researchers have cracked one of the secrets of tooth decay. The materials scientists are the first to identify a small number of impurity atoms in human enamel that may contribute to the material's strength but also make it more soluble. They also are the first to determine the spatial distribution of the impurities with atomic-scale resolution. The discovery could lead to a better understanding of human tooth decay as well as genetic conditions that affect enamel formation.

  • Tongue microbes provide window to heart health

    Microorganisms on the tongue could help diagnose heart failure, according to new research. 'The tongues of patients with chronic heart failure look totally different to those of healthy people,' said one of the researchers.

  • Could the cure for IBD be inside your mouth?

    A new collaborative study reveals that inflammatory bowel disease (IBD) may be the latest condition made worse by poor oral health via a clash between the mouth and gut microbiomes.

  • Harnessing pickle power to promote dental health

    A research team evaluated 14 different types of Sichuan pickles from southwest China. They extracted 54 different strains of Lactobacilli and found that one, L. plantarum K41, significantly reduced the incidence and severity of cavities. K41 was also highly tolerant of acids and salts, an additional benefit as a probiotic for harsh oral conditions. It also could have potential commercial value when added to dairy products.

  • Cavity-causing bacteria assemble an army of protective microbes on human teeth

    It's not just the presence of bacteria that can lead to disease; their spatial arrangement also matters. When scientists examined the bacteria that causes tooth decay, they found it 'shields' itself under blankets of sugars and other bacteria in a crown-like arrangement, helping it evade antimicrobials and concentrate its tooth-damaging acids.

  • Fluoride in water is not associated with increase in osteosarcoma

    The results of a new study demonstrated that community water fluoridation is not associated with increased risk of osteosarcoma.

  • Immune-regulating drug improves gum disease in mice

    A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study.

  • AI to make dentists' work easier

    Researchers have developed a new automatized way to localize mandibular canals.

  • Improving the treatment of periodontitis

    For the first time, researchers have shown that a unicellular parasite commonly found in the mouth plays a role in both severe tissue inflammation and tissue destruction.

  • Teeth serve as 'archive of life,' new research finds

    Teeth constitute a permanent and faithful biological archive of the entirety of the individual's life, from tooth formation to death, a team of researchers has found. Its work provides new evidence of the impact that events, such as reproduction and imprisonment, have on an organism.

  • Commonly used mouthwash could make saliva significantly more acidic, change microbes

    The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria that lower saliva pH, and may increase the risk of tooth damage. "In the face of the recent COVID-19 outbreak many dentists are now using chlorhexidine as a pre-rinse before doing dental procedures. We urgently need more information on how it works on viruses," said one of the researchers.

  • Stem cells and nerves interact in tissue regeneration and cancer progression

    Researchers show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies.

  • Ouch: Patients prescribed opioids after tooth extraction report worse pain

    The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say researchers.

  • Researchers discover tooth-enamel protein in eyes with dry AMD

    A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a new study.

  • Not only what you eat, but how you eat, may affect your microbiome

    Researchers found that post-stroke patients re-grow a healthy microbiota in their mouth and gut when they revert to normal food intake from tube feeding. These results emphasize the need to actively normalize feeding in these patients, not only to minimize the risks of tube feeding, but also because oral feeding significantly alters the microbiome of both the mouth and the gut, potentially with beneficial consequences for overall health.

  • The microbes in your mouth, and a reminder to floss and go to the dentist

    Most people know that good oral hygiene -- brushing, flossing, and regular dental visits -- is linked to good health. Microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth. Their study found a correlation between people who did not visit the dentist regularly and increased presence of a pathogen that causes periodontal disease.

  • Could this plaque identifying toothpaste prevent a heart attack or stroke?

    For decades, researchers have suggested a link between oral health and inflammatory diseases affecting the entire body -- in particular, heart attacks and strokes. Results of a randomized pilot trial of Plaque HD®, the first toothpaste that identifies plaque so that it can be removed with directed brushing, showed that it produced a statistically significant reduction in C-reactive protein, a sensitive marker for future risks of heart attacks and strokes, among those with elevations at baseline.

  • How too much fluoride causes defects in tooth enamel

    Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel -- a novel explanation for how dental fluorosis, a condition caused by overexposure to fluoride during childhood, arises.

  • Chemical found in drinking water linked to tooth decay in children

    Children with higher concentrations of a certain chemical in their blood are more likely to get cavities, according to a new study. Researchers found that higher concentrations of PFAS were associated with greater tooth decay in children.

  • Why eating yogurt may help lessen the risk of breast cancer

    One of the causes of breast cancer may be inflammation triggered by harmful bacteria suggest researchers. Scientists advise consuming natural yogurt, which contains beneficial bacteria which dampens inflammation and which is similar to the bacteria found in breastfeeding mothers. Their suggestion is that this bacteria is protective because breast feeding reduces the risk of breast cancer. The consumption of yogurt is also associated with a reduction in the risk of breast cancer.

  • Preventing, healing tooth decay with a bioactive peptide

    Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful, but untreated caries could lead to worse pain, tooth loss, infection, and even illness or death. Now, researchers report a bioactive peptide that coats tooth surfaces, helping prevent new cavities and heal existing ones in lab experiments.

  • Ancient 'chewing gum' yields insights into people and bacteria of the past

    Researchers have succeeded in extracting a complete human genome from a thousands-of-years old 'chewing gum.' According to the researchers, it is a new untapped source of ancient DNA.

  • Link between obesity and gum disease

    Obesity and gum (periodontal) disease are among the most common non-communicable diseases in the United States -- and studies show these chronic conditions may be related. This new study explores the effect of obesity on non-surgical periodontal care and evaluates potential pathways that may illustrate the connection between the two conditions.

  • Brush your teeth to protect the heart

    Brushing teeth frequently is linked with lower risks of atrial fibrillation and heart failure, according to a new study.

  • Experts call for more active prevention of tooth decay for children's teeth

    Three-year trial comparing three treatment strategies for tooth decay in children's teeth finds no evidence to suggest that conventional fillings are more successful than sealing decay into teeth, or using preventive methods alone. 43% of those participating in the study experienced toothache or dental infection regardless of the treatment received.

  • First adult molars are 'living fossils' that hold a 'health record' dating back to the womb

    Researchers have found that a person's first permanent molars carry a life-long record of health information dating back to the womb, storing vital information that can connect maternal health to a child's health, even hundreds of years later.

  • Milk from teeth: Dental stem cells can generate milk-producing cells

    Stem cells of the teeth can contribute to the regeneration of non-dental organs, namely mammary glands. According to a new study, dental epithelial stem cells from mice can generate mammary ducts and even milk-producing cells when transplanted into mammary glands. This could be used for post-surgery tissue regeneration in breast cancer patients.

  • Temporomandibular Joint Disorder

    Temporomandibular joint disorder (TMD) describes a variety of conditions that affect jaw muscles, temporomandibular joints and nerves associated with chronic facial pain. Symptoms may occur on one or both sides of the face, head or jaw, or develop after an injury. TMD affects more than twice as many women than men.    Updated: November 2008   

  • What is Dental Amalgam (Silver Filling)?

    What is Dental Amalgam (Silver Fillings)?   Most people recognize dental amalgams as silver fillings. Dental amalgam is a mixture of mercury, silver, tin and copper. Mercury, which makes up about 50 percent of the compound, is used to bind the metals together and to provide a strong, hard, durable filling. After years of research, mercury has been found to be the only eleme...

  • What is Orofacial Pain?

    Orofacial pain includes a number of clinical problems involving the chewing (masticatory) muscles or temporomandibular joint. Problems can include temporomandibular joint discomfort; muscle spasms in the head, neck and jaw; migraines, cluster or frequent headaches; or pain with the teeth, face or jaw.   You swallow approximately 2,000 times per day, which causes the upper and lower teeth t...

  • What is a Composite Resin (White Filling)?

    What is a Composite Resin (White Filling)?   A composite filling is a tooth-colored plastic and glass mixture used to restore decayed teeth. Composites are also used for cosmetic improvements of the smile by changing the color of the teeth or reshaping disfigured teeth.   How is a composite placed?   Following preparation, the dentist ...

  • Are You Biting Off More Than You Can Chew?

    In our fast-paced lives, many of us may be eating in a hurry, taking giant bites of our food to get done quickly and on to the next task. Fast-food restaurants advertise giant burgers and sandwiches as a selling point, but often those super-sized delicacies are larger than a human mouth.   Taking bites that are too big to chew could be bad for your jaw and teeth, says the Academy of Genera...

  • The History of Dental Advances

    The History of Dental Advances   Many of the most common dental tools were used as early as the Stone Age. Thankfully, technology and continuing education have made going to the dentist a much more pleasant – and painless – experience. Here is a look at the history of dentistry's most common tools, and how they came to be vital components of our oral health care needs.   Where did t...

  • Check Menstrual Calendar for Tooth Extraction

    Dry socket, the most common postoperative complication from tooth extractions, delays the normal healing process and results when the newly formed blood clot in the extraction site does not form correctly or is prematurely lost. This blood clot lays the foundation for new tissue and bone to develop over a two-month healing process.   Updated: October 2008    

  • Headaches and Jaw Pain? Check Your Posture!

    If you experience frequent headaches and pain in your lower jaw, check your posture and consult your dentist about temporomandibular disorder (TMD), recommends the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education.   Poor posture places the spine in a position that causes stress to the jaw joint. When people slouch or hunch over...

  • Men: Looking for a Better Job? Start by Visiting the Dentist

    Men: Looking for a Better Job? Start by Visiting the Dentist   An online poll of 289 general dentists and consumers confirms the traditional stereotype that men are less likely to visit the dentist than their female counterparts, according to the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education.   Why? Nearly 45 percent...

  • Why is Oral Health Important for Men?

    Why is Oral Health Important for Men?   Men are less likely than women to take care of their physical health and, according to surveys and studies, their oral health is equally ignored. Good oral health recently has been linked with longevity. Yet, one of the most common factors associated with infrequent dental checkups is just being male. Men are less likely than women to seek preventive ...

  • What is Baby Bottle Tooth Decay?

    What is Baby Bottle Tooth Decay?   Baby bottle tooth decay is caused by the frequent and long-term exposure of a child's teeth to liquids containing sugars. Among these liquids are milk, formula, fruit juice, sodas and other sweetened drinks. The sugars in these liquids pool around the infant's teeth and gums, feeding the bacteria in plaque. Every time a child consumes a sugary liquid, acid...

  • Pacifiers Have Negative and Positive Effects

    Pacifiers Have Negative and Positive Effects   It’s one of the hardest habits to break and can require a great deal of persuasion: Parents often struggle with weaning their child off of a pacifier.   There is much debate regarding the use of pacifiers, but there is evidence to show that there are both pros and cons, according to a study in the January/February 2007 issue of Gene...

  • Is My Child at Risk for Early Childhood Tooth Decay?

    Is My Child at Risk for Early Childhood Tooth Decay?   The average healthy adult visits the dentist twice a year. The average healthy 2-year-old has never been to the dentist. By kindergarten, 25 percent of children have never seen a dentist, yet dental decay is the single most common chronic childhood disease in America.   The culprit? A combination of misinformation about when a c...

  • When Should My Child First See a Dentist?

    When Should My Child First See a Dentist?   Your child's first visit to the dentist should happen before his or her first birthday. The general rule is six months after eruption of the first tooth. Taking your child to the dentist at a young age is the best way to prevent problems such as tooth decay, and can help parents learn how to clean their child's teeth and identify his or her fluori...

  • How Do I Care for My Child's Baby Teeth?

    How Do I Care for My Child’s Baby Teeth?   Though you lose them early in life, your primary teeth, also called baby teeth, are essential in the development and placement of your permanent teeth. Primary teeth maintain the spaces where permanent teeth will erupt and help develop proper speech patterns that would otherwise be difficult; without maintenance of these spaces, crowding and misali...

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