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- How oral bacteria suppress protection against viral growth
Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection.
- Researchers gain insights into how ultrasmall bacteria from the environment have adapted to live inside humans
Scientists created a model system to experimentally study tiny bacteria called TM7 and provide empirical data to confirm a hypothesis for how the bacteria adapted to live inside humans.
- Disarming a blood-clotting protein prevents gum disease in mice
Blocking function of a blood-clotting protein, called fibrin, prevented bone loss from periodontal (gum) disease in mice, according to new research. The study suggests that suppressing abnormal fibrin activity could hold promise for preventing or treating periodontal disease, as well as other inflammatory disorders marked by fibrin buildup, including arthritis and multiple sclerosis.
- Gum disease increases risk of other illness such as mental health and heart conditions, study suggests
A new study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of gum disease.
- A chewing gum that could reduce SARS-CoV-2 transmission
In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus, according to scientists.
- Obesity raises the risk of gum disease by inflating growth of bone-destroying cells
Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new research that sought to improve understanding of the connection between obesity and gum disease. The study, completed in an animal model and published in October in the Journal of Dental Research, found that excessive inflammation resulting from obesity raises the number of myeloid-derived suppressor cells (MDSC), a group of immune cells that increase during illness to regulate immune function. MDSCs, which originate in the bone marrow, develop into a range of different cell types, including osteoclasts (a cell that breaks down bone tissue).
- Baby teeth may one day help identify kids at risk for mental disorders later in life
The thickness of growth marks in primary (or 'baby') teeth may help identify children at risk for depression and other mental health disorders later in life, according to a ground-breaking investigation.
- ‘Nanozyme’ therapy prevents harmful dental plaque build-up
FDA-approved iron oxide nanoparticles, delivered in a mouth rinse, can suppress the growth of dental plaque and kill bacteria responsible for tooth decay, according to a new study. The nanoparticles act as enzymes to activate hydrogen peroxide in a way that precisely targets harmful microbes and spares normal tissue.
- New technique helps researchers understand how acid damages teeth
Researchers have developed a new technique to improve understanding of how acid damages teeth at the microstructural level.
- Heartburn drugs may have unexpected benefits on gum disease
New research found that patients who used drugs prescribed to treat heartburn, acid reflux and ulcers were more likely to have smaller probing depths in the gums (the gap between teeth and gums).
- A study of skull growth and tooth emergence reveals that timing is everything
Paleoanthropologists have wondered how and why humans evolved molars that emerge into the mouth at specific ages and why those ages are so delayed compared to living apes. It is the coordination between facial growth and the mechanics of the chewing muscles that determines not just where but when adult molars emerge. This results in molars coming in only when enough of a 'mechanically safe' space is created. Molars that emerge 'ahead of schedule' would do so in a space that, when chewed on, would disrupt the fine-tuned function of the entire chewing apparatus by causing damage to the jaw joint.
- Dental care: The best, worst and unproven tools to care for your teeth
Only a handful of oral hygiene tools actually prevent gum disease. At the moment, all other tools are only supported by insufficient evidence, say researchers.
- Smart dental implants
Researchers are developing a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing to power a tissue-rejuvenating light. The innovation could extend the usable life of an implant.
- Whiter teeth, without the burn
Researchers report that they have developed a gel that, when exposed to near infrared (NIR) light, safely whitens teeth without the burn.
- Dental implant surfaces play major role in tissue attachment, warding off unwanted bacteria
The surface of implants, as well as other medical devices, plays a significant role in the adsorption of oral proteins and the colonization by unwanted microorganisms (a process known as biofouling), according to a new study.
- Setting the teeth on edge: Identifying the risk factors for tooth loss
Periodontitis, a form of severe gum infection, can lead to tooth loss and is linked with other diseases. Management of periodontitis remains difficult, partly due to inadequate understanding of risk factors associated with the condition. In a recent study from Japan, researchers have emphasized the role of oral microbiome, over an individual's genetic makeup, in the development of the disease, providing clinicians a guide to designing strategies for diagnosing and treating periodontitis.
- Research finds ‘very low rates’ of dental fluoride varnish treatment for young children
Fewer than 5% of well-child visits for privately insured young children included a recommended dental fluoride varnish application, despite mandatory insurance coverage for this service, according to a new study.
- Half of pediatric opioid prescriptions are 'high risk'
A new study suggests that children and young adults are frequently exposed to unsafe opioid prescriptions.
- Light therapy helps burn injuries heal faster by triggering growth protein
The research found that photobiomodulation -- a form of low-dose light therapy -- sped up recovery from burns and reduced inflammation in mice by activating a protein that controls cell growth and division.
- Good toothbrushing habits in children linked to mother's wellbeing
Researchers have shown that postpartum depression can inhibit a mother's ability to instill healthy tooth brushing habits in children. The study demonstrates the need to foster greater mental support and management for mothers and incorporate these factors when assessing children's oral health.
- Study reveals new aspects of gingivitis and body's response
Researchers have identified and classified how different people respond to the accumulation of dental plaque.
- Tooth loss associated with increased cognitive impairment, dementia
Tooth loss is a risk factor for cognitive impairment and dementia -- and with each tooth lost, the risk of cognitive decline grows, according to a new analysis.
- Mucus and mucins may become the medicine of the future
The body is filled with mucus that keeps track of the bacteria. Now, researchers present a method for producing artificial mucus. They hope that the artificial mucus, which consists of sugary molecules, may help to develop completely new, medical treatments.
- New report aims to improve VR use in healthcare education
A new report could help improve how immersive technologies such as Virtual Reality (VR) and Augmented Reality (AR) are used in healthcare education and training.
- Pulling wisdom teeth can improve long-term taste function, research finds
Patients who had their wisdom teeth extracted had improved tasting abilities decades after having the surgery, according to a new study.
- Predicting tooth loss
New research suggests that machine learning tools can help identify those at greatest risk for tooth loss and refer them for further dental assessment in an effort to ensure early interventions to avert or delay the condition.
- Gaps to fill: Income, education may impact inequalities in seeking dental care
A study examined a massive national claims dataset in search of regional and socioeconomic inequalities in the use of dental care services in Japan. This examination of millions of pieces of data found periodontal care and outreach services showed the widest regional inequalities. People in areas with lower education and income were more likely to seek treatment after dental diseases progress. More clinics and higher education and incomes correlated with earlier treatment.
- A link between childhood stress and early molars
Research shows that children from lower-income backgrounds and those who go through greater adverse childhood experiences get their first permanent molars sooner. The findings align with a broader pattern of accelerated development often seen under conditions of early-life stress.
- Rare mineral from rocks found in mollusk teeth
Researchers discovered a rare mineral hidden inside the teeth of a chiton, a large mollusk found along rocky coastlines. Before this strange surprise, the iron mineral, called santabarbaraite, only had been documented in rocks.
- A gentler strategy for avoiding childhood dental decay
By targeting the bonds between bacteria and yeast that can form a sticky dental plaque, a new therapeutic strategy could help wash away the build-up while sparing oral tissues, according to a new study.
- Dental procedures during pandemic are no riskier than a drink of water, study finds
A new study's findings dispel the misconception that patients and providers are at high risk of catching COVID-19 at the dentist's office.
- AI helps predict treatment outcomes for patients with diseased dental implants
Peri-implantitis, a condition where tissue and bone around dental implants becomes infected, besets roughly one-quarter of dental implant patients, and currently there's no reliable way to assess how patients will respond to treatment of this condition.
- Independent evolutionary origins of vertebrate dentitions
The origins of a pretty smile have long been sought in the fearsome jaws of living sharks which have been considered living fossils reflecting the ancestral condition for vertebrate tooth development and inference of its evolution. However, this view ignores real fossils which more accurately reflect the nature of ancient ancestors.
- Comprehensive single-cell atlas of human teeth
Researchers have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.
- Study shows 2 percent of asymptomatic pediatric dental patients test positive for COVID-19
A new study has shown a novel way to track potential COVID-19 cases -- testing children who visit the dentist. The study also showed an over 2 percent positivity rate for the asymptomatic children tested.
- Good dental health may help prevent heart infection from mouth bacteria
Good oral hygiene and regular dental care are the most important ways to reduce risk of a heart infection called infective endocarditis caused by bacteria in the mouth. There are four categories of heart patients considered to be at highest risk for adverse outcomes from infective endocarditis, and only these patients are recommended to receive preventive antibiotic treatment prior to invasive dental procedures.
- Imbalance in gum bacteria linked to Alzheimer's disease biomarker
Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta -- a key biomarker for Alzheimer's disease -- in their cerebrospinal fluid, according to new research. However, this imbalance in oral bacteria was not associated with another Alzheimer's biomarker called tau.
- New drug to regenerate lost teeth
Scientists report that an antibody for one gene -- uterine sensitization associated gene-1 or USAG-1 -- can stimulate tooth growth in mice suffering from tooth agenesis.
- People with severe gum disease may be twice as likely to have increased blood pressure
Research shows that periodontitis, severe gum disease, is linked to higher blood pressure in otherwise healthy individuals. This study of 500 adults with and without gum disease found that approximately 50% of adults could have undetected hypertension. Promotion of good oral health could help reduce gum disease and the risk of high blood pressure and its complications.
- How teeth sense the cold
An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches.
- Scientists find evidence that novel coronavirus infects the mouth's cells
Scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. The findings point to the possibility that the mouth plays a role in transmitting SARS-CoV-2 to the lungs or digestive system via saliva laden with virus from infected oral cells. A better understanding of the mouth's involvement could inform strategies to reduce viral transmission within and outside the body.
- Dentists' tool boost as engineers get to root of tiny bubbles
People's teeth-chattering experiences in the dentist's chair could be improved by fresh insights into how tiny, powerful bubbles are formed by ultra-fast vibrations, a study suggests.
- Periodontal disease increases risk of major cardiovascular events
People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research.
- New hope for treating chronic pain without opioids
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients -- a frustration that's often compounded by a hesitation to prescribe opioids for pain.
- Bleeding gums may be a sign you need more vitamin C in your diet
Bleeding of the gums on gentle probing, or gingival bleeding tendency, and also bleeding in the eye, or retinal hemorrhaging, were associated with low vitamin C levels in the bloodstream.
- Ancient proteins help track early milk drinking in Africa
Got milk? The 1990s ad campaign highlighted the importance of milk for health and wellbeing, but when did we start drinking the milk of other animals? And how did the practice spread? A new study led by scientists from Germany and Kenya highlights the critical role of Africa in the story of dairying, showing that communities there were drinking milk by at least 6,000 years ago.
- Research establishes antibiotic potential for cannabis molecule
The main nonpsychoactive component of cannabis has been shown to kill the bacteria responsible for gonorrhoea, meningitis and legionnaires disease, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.
- Research shapes safe dentistry during COVID-19
Research has been used to shape how dentistry can be carried out safely during the COVID-19 pandemic by mitigating the risks of dental aerosols.
- Gum disease-causing bacteria borrow growth molecules from neighbors to thrive
The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new study.
- Dental experts discover biological imbalance is the link between gum and kidney disease
An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study has found.
- The incredible, variable bacteria living in your mouth
Researchers have examined the human oral microbiome and discovered tremendous variability in bacterial subpopulations living in certain areas of the mouth. In many cases, the team was able to identify a handful of genes that might explain a particular bacterial group's habitat specificity.
- Coronavirus spread during dental procedures could be reduced with slower drill rotation
Researchers have found that careful selection and operation of dental drills can minimize the spread of COVID-19 through aerosols.
- How poor oral hygiene may result in metabolic syndrome
Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.
- Reversible stickiness is something to smile about
Researchers report a cross-linker for dental cement that breaks down under UV light, making treatments easier to reverse.
- Can we make bones heal faster?
A new article describes for the first time how minerals come together at the molecular level to form bones and other hard tissues, like teeth and enamel.
- Teeth grinding and facial pain increase due to coronavirus stress and anxiety
The stress and anxiety experienced by the general population during Israel's first lockdown brought about a significant rise in orofacial and jaw pain, as well as jaw-clenching in the daytime and teeth-grinding at night, according to a new study.
- Most dentists have experienced aggression from patients
Roughly half of US dentists experienced verbal or reputational aggression by patients in the past year, and nearly one in four endured physical aggression, according to a new study.
- A tiny jaw from Greenland sheds light on the origin of complex teeth
Scientists have described the earliest known example of dentary bone with two rows of cusps on molars and double-rooted teeth. The new findings offer insight into mammal tooth evolution, particularly the development of double-rooted teeth.
- Mechanical forces of biofilms could play role in infections
Studying bacterial biofilms, scientists have discovered that mechanical forces within them are sufficient to deform the soft material they grow on, e.g. biological tissues, suggesting a 'mechanical' mode of bacterial infection.
- Light stimulation makes bones heavier
Researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery.
- Temporomandibular Joint Disorder
Temporomandibular joint disorder (TMD) describes a variety of conditions that affect jaw muscles, temporomandibular joints and nerves associated with chronic facial pain. Symptoms may occur on one or both sides of the face, head or jaw, or develop after an injury. TMD affects more than twice as many women than men. Updated: November 2008
- What is Dental Amalgam (Silver Filling)?
What is Dental Amalgam (Silver Fillings)? Most people recognize dental amalgams as silver fillings. Dental amalgam is a mixture of mercury, silver, tin and copper. Mercury, which makes up about 50 percent of the compound, is used to bind the metals together and to provide a strong, hard, durable filling. After years of research, mercury has been found to be the only eleme...
- What is Orofacial Pain?
Orofacial pain includes a number of clinical problems involving the chewing (masticatory) muscles or temporomandibular joint. Problems can include temporomandibular joint discomfort; muscle spasms in the head, neck and jaw; migraines, cluster or frequent headaches; or pain with the teeth, face or jaw. You swallow approximately 2,000 times per day, which causes the upper and lower teeth t...
- What is a Composite Resin (White Filling)?
What is a Composite Resin (White Filling)? A composite filling is a tooth-colored plastic and glass mixture used to restore decayed teeth. Composites are also used for cosmetic improvements of the smile by changing the color of the teeth or reshaping disfigured teeth. How is a composite placed? Following preparation, the dentist ...
- Are You Biting Off More Than You Can Chew?
In our fast-paced lives, many of us may be eating in a hurry, taking giant bites of our food to get done quickly and on to the next task. Fast-food restaurants advertise giant burgers and sandwiches as a selling point, but often those super-sized delicacies are larger than a human mouth. Taking bites that are too big to chew could be bad for your jaw and teeth, says the Academy of Genera...
- The History of Dental Advances
The History of Dental Advances Many of the most common dental tools were used as early as the Stone Age. Thankfully, technology and continuing education have made going to the dentist a much more pleasant – and painless – experience. Here is a look at the history of dentistry's most common tools, and how they came to be vital components of our oral health care needs. Where did t...
- Check Menstrual Calendar for Tooth Extraction
Dry socket, the most common postoperative complication from tooth extractions, delays the normal healing process and results when the newly formed blood clot in the extraction site does not form correctly or is prematurely lost. This blood clot lays the foundation for new tissue and bone to develop over a two-month healing process. Updated: October 2008
- Headaches and Jaw Pain? Check Your Posture!
If you experience frequent headaches and pain in your lower jaw, check your posture and consult your dentist about temporomandibular disorder (TMD), recommends the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education. Poor posture places the spine in a position that causes stress to the jaw joint. When people slouch or hunch over...
- Men: Looking for a Better Job? Start by Visiting the Dentist
Men: Looking for a Better Job? Start by Visiting the Dentist An online poll of 289 general dentists and consumers confirms the traditional stereotype that men are less likely to visit the dentist than their female counterparts, according to the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education. Why? Nearly 45 percent...
- Why is Oral Health Important for Men?
Why is Oral Health Important for Men? Men are less likely than women to take care of their physical health and, according to surveys and studies, their oral health is equally ignored. Good oral health recently has been linked with longevity. Yet, one of the most common factors associated with infrequent dental checkups is just being male. Men are less likely than women to seek preventive ...
- What is Baby Bottle Tooth Decay?
What is Baby Bottle Tooth Decay? Baby bottle tooth decay is caused by the frequent and long-term exposure of a child's teeth to liquids containing sugars. Among these liquids are milk, formula, fruit juice, sodas and other sweetened drinks. The sugars in these liquids pool around the infant's teeth and gums, feeding the bacteria in plaque. Every time a child consumes a sugary liquid, acid...
- Pacifiers Have Negative and Positive Effects
Pacifiers Have Negative and Positive Effects It’s one of the hardest habits to break and can require a great deal of persuasion: Parents often struggle with weaning their child off of a pacifier. There is much debate regarding the use of pacifiers, but there is evidence to show that there are both pros and cons, according to a study in the January/February 2007 issue of Gene...
- Is My Child at Risk for Early Childhood Tooth Decay?
Is My Child at Risk for Early Childhood Tooth Decay? The average healthy adult visits the dentist twice a year. The average healthy 2-year-old has never been to the dentist. By kindergarten, 25 percent of children have never seen a dentist, yet dental decay is the single most common chronic childhood disease in America. The culprit? A combination of misinformation about when a c...
- When Should My Child First See a Dentist?
When Should My Child First See a Dentist? Your child's first visit to the dentist should happen before his or her first birthday. The general rule is six months after eruption of the first tooth. Taking your child to the dentist at a young age is the best way to prevent problems such as tooth decay, and can help parents learn how to clean their child's teeth and identify his or her fluori...
- How Do I Care for My Child's Baby Teeth?
How Do I Care for My Child’s Baby Teeth? Though you lose them early in life, your primary teeth, also called baby teeth, are essential in the development and placement of your permanent teeth. Primary teeth maintain the spaces where permanent teeth will erupt and help develop proper speech patterns that would otherwise be difficult; without maintenance of these spaces, crowding and misali...